# Senior R&D Manager

> Eva Pharma · Giza, Egypt · Full-time · Posted 2026-06-04

**Workplace:** on_site

**Department:** R&D Business Division

## Description

EVA Pharma is hiring Analytical Expert within R&D Analytical Development. The role drives analytical method development, characterisation, validation, stability, and technology transfer across small molecules, Peptides, DPI, Gels, and Patches — while coaching and coordinating a team of analysts. 

**Key responsibiities:**

**Method Development & Validation**

-   Develop and optimise HPLC/UPLC and dissolution methods for DS and DP across Solids, Steriles, Peptides, DPI, Gels, and Patches 

-   Execute full ICH Q2(R1) method validation: specificity, linearity, accuracy, precision, robustness, LOD/LOQ 

-   Author validation reports and maintain lifecycle documentation 

**Characterisation & Impurity Profiling** 

-   Lead physicochemical and solid-state characterisation of DS and DP 

-   Conduct impurity profiling and forced degradation studies per ICH Q3A/Q3B 

-   Characterise Gel and Patch products: rheology, release rate, drug migration, adhesion, and skin permeation 

-   Profile Peptide APIs: identity, purity, aggregation, and sequence confirmation 

-   Support DPI characterisation: APSD via NGI/ACI, fine particle fraction, and blend uniformity 

**Bioassay Support** 

-   Support development and qualification of bioassay methods for potency and biological activity 

-   Review and interpret bioassay data for batch release and stability 

**Stability Studies** 

-   Design and execute stability protocols per ICH Q1A–Q1F for DS and DP 

-   Manage sampling plans, testing schedules, and data interpretation 

-   Author shelf-life justification and stability summary reports for regulatory submissions 

**Dissolution Method Development** 

-   Develop biorelevant dissolution methods for solid, semi-solid (Gels), and transdermal (Patch) dosage forms 

-   Validate dissolution methods and establish acceptance criteria per ICH/Ph. Eur./USP 

**Tech Transfer to QC** 

-   Lead method transfer from R&D to QC: protocols, acceptance criteria, and inter-lab comparison 

-   Train QC analysts on transferred methods and resolve technical discrepancies 

-   Ensure complete, audit-ready transfer documentation 

**Regulatory & CMC Support** 

-   Contribute analytical sections to CTAs, MAAs, DMFs, and local dossiers 

-   Prepare validation reports, specifications, and analytical justifications 

-   Support regulatory queries and inspection readiness 

**Team Leadership & Mentorship** 

-   Lead and coordinate a team of 3–6 analysts: priorities, workload, and delivery tracking 

-   Coach analysts through technical challenges, troubleshooting, and data interpretation 

-   Conduct regular feedback sessions and support individual development plans 

-   Foster scientific discipline, accuracy, and continuous improvement

## Requirements

**Education:**

Master's or PhD in Pharmaceutical Sciences, Analytical Chemistry, or related field 

**Overall Experience:**

 10–15 years in pharmaceutical analytical development (R&D environment), 2–3 years leading or coordinating a small analytical team or project group 

**Technical skills:** 

-   HPLC/UPLC method development and validation — minimum 6–8 years hands-on 

-   Impurity profiling, forced degradation, and stability studies per ICH guidelines 

-   Dissolution method development for solid, semi-solid (Gel), and transdermal (Patch) dosage forms 

-   Gel and Patch characterisation: release rate, rheology, adhesion, permeation 

-   Peptide or DPI analytical characterisation 

-   Analytical method transfer to QC with formal transfer protocols 

-   Contribution to at least one regulatory dossier (CTA, MAA, or local registration)

## Apply

[Apply at Eva Pharma](https://apply.workable.com/eva-pharma/j/D2C7335920/apply)

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